Tuesday: Stability of Secondary Structure
Goals of the day - Stabilization of secondary structure. Tertiary structure and the hydrophobic core.

• My lecture notes on protein tertiary and quaternary structure
• Read V&V Ch. 4, 7.1, 7.5 or G&G Ch. 4-5
• My powerpoint slides
• Additional Reading
• Patigri et al. (2007) Hydrogen Bond Surrogate Approach for Stabilization of Short Peptide Sequences.

Thursday: Stability of tertiary folds, quaternary structure and PyMOL time!
Goals of the day - Measuring stability of tertiary structure, some case studies. Quaternary structure.

• My lecture notes protein stability are coming...
• Read V&V Ch. 8 or G&G Ch. 6
• My powerpoint slides
• Additional Reading
• V. Bloomfield's on-line notes on thermodynamics.
• Nice review by N. Pace on stability